Tuberculosis prevention must integrate technological and basic care innovation

some patients (as in our case) clofazimine represents the only effective drug, exclusion of clofazimine from salvage therapy would greatly limit treatment efficacy. Patients due to receive a regimen with QT prolonging drugs (i.e. bedaquiline, delamanid, clofazimine and moxifloxacin) alone or in combination should receive ECG and electrolytes monitoring before and during treatment, so as not to lose therapeutic benefit. If QTc prolungation above 500 ms occurs, one of the QTc prolonging drugs should be promptly discontinued.